Best Antifungal Creams – Buyer’s Guide and Reviews

Many people suffer from a variety of different antifungal ailments.

These conditions range from athlete’s foot to jock itch, to ringworm, and also include less common ailments.

Thus, there are many people wondering what the best antifungal cream is.

This article will compare and contrast 10 different creams.

Best Antifungal Creams 2019

Clotrimazole Antifungal Cream %1
(Editor's Choice)
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Miconazole Nitrate 2%
(Editor's Choice)
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Medline Remedy Olivamine Antifungal Cream Check Price
Family Care Tolnaftate Antifungal Cream 1% 3 Pack Check Price
Lotrimin Antifungal Ringworm Cream Check Price
Lamisil Athlete's Foot Antifungal Cream, Full Prescription Strength Check Price
Pro-Ex Antifungal Cream Clotrimazole 1% 7.5 oz Total Check Price
Derman Antifungal Cream 6 Pack Check Price
Soothe & Cool Inzo Antifungal Cream Check Price
Kerasal Complete Care 2 in 1 Nail, Toe & Foot Antifungal Treatment Cream Check Price

1) Clotrimazole Antifungal Cream 1%


Clotrimazole antifungal cream is one of the most popular antifungal creams, and for good reason. This product has been scientifically proven to fight effectively against jock itch, ringworm, and athlete’s foot. These are the most common fungal conditions, so most people will be helped by this product. This item is the generic version of clotrimazole, so it has the same effect but is cheaper than the brand name.


  • Very effective on the most common fungal conditions
  • Relatively few side effects compared to other antifungal creams
  • Very affordable price compared to brand name products


  • Limited effectiveness on conditions other than jock itch, ringworm, and athlete’s foot
  • Some people report side effects like redness and irritation
  • Clotrimazole can take as long as a month to get rid of persistant fungal conditions

2) Miconazole Nitrate 2%


Miconazole nitrate is another very popular and effective antifungal treatment. It is especially known for treating jock itch. However, it can also be used to treat ringworm and jock itch. Miconazole nitrate is commonly known simply as miconazole. It has been around for decades, and as such is offered as a generic.


  • Miconazole nitrate may be the best antifungal for jock itch
  • Miconazole is readily available as a generic, so it is quite affordable
  • Miconazole is known to work faster than many antifungals


  • It is slightly more expensive than other antifungals like clotrimazole
  • Miconazole is not as effective for ringworm and athlete’s foot
  • It is slightly more likely to cause negative side effects

3) Medline Remedy Olivamine Antifungal Cream


This cream is unique compared to most of the other items on this list. It is all natural, while the other products feature manmade medicines. Many people these days are looking for natural alternatives to traditional manmade products. This is especially true for skincare products. The Medline Remedy cream uses olivamine and aloe vera as its main ingredients, and both are natural.


  • All natural product that causes fewer negative side effects
  • Also soothes redness and irritation not caused by fungal conditions
  • Does treat a wide variety of different fungal conditions


  • This item is slightly more expensive than traditional antifungals
  • It does not have as much scientific evidence proving its effectiveness as other products
  • Some reviews note that it can take longer to work as compared to similar products

4) Family Care Tolnaftate Antifungal Cream 1% 3 Pack


This generic tolnaftate cream is a favorite of reviewers, and it is easy to see why. It features tolnaftate as its active ingredient, and tolnaftate is scientifically proven to be one of the most effective over the counter antifungals, especially against athlete’s foot. As previously mentioned, it is a generic. This means it is much less expensive than a name brand.


  • Tolnaftate is proven to be very effective against athlete’s foot
  • This generic tolnaftate product is quite cheap
  • Tolnaftate is known to be relatively gentle on the skin


  • This product is known to not be quite as effective against ringworm or jock itch
  • Tolnaftate can take a while to work
  • Many people will not need the whole 3 pack

5) Lotrimin Antifungal Ringworm Cream


This is the first brand name product on the list, and it is one of the most well-known brands in the industry. This cream is specifically targeted towards ringworm, although it can be used for athlete’s foot and jock itch. The active ingredient in this product is clotrimazole, which is a well-known and effective antifungal.


  • This brand name product may have higher quality ingredients
  • The peace of mind that comes with an established brand
  • More informative packaging


  • This item is slightly more expensive than generics
  • This product is targeted towards ringworm and may not be as effective for other conditions
  • Some reviews report side effects like redness and irritation

6) Lamisil Athlete’s Foot Antifungal Cream, Full Prescription Strength


The second brand name product on this list is aimed at athlete’s foot, in contrast with the Lotrimin product aimed at ringworm. this Lamisil product is a little different in that the active ingredient is terbinafine hydrochloride. This is known for being very strong, and for more commonly being found in prescription products.


  • This is one of the strongest over the counter products you can get
  • This item may save you an expensive trip to the doctor
  • This product is much more convenient to obtain than a prescription


  • This item is quite expensive
  • It is known to cause side effects more frequently than other products
  • These side effects may be more severe

7) Pro-Ex Antifungal Cream Clotrimazole 1% 7.5 oz Total


This product is an all-around antifungal that features clotrimazole as its main ingredient. This is a characteristic shared with several of the other products on this list. The main thing that helps this item stand out is that it is a 5 pack of clotrimazole-based antifungal, with a total amount of 7.5 ounces. The large amount of cream means that it is the best antifungal cream jock itch.


  • There is enough antifungal cream to treat the most persistent of conditions
  • This product is quite affordable
  • The reviews for this item are very good


  • Some people may not need all of the antifungal cream included in this product
  • Clotrimazole is known to have side effects like redness and irritation
  • People may be tempted to use too much of the cream, which could result in side effects

8) Derman Antifungal Cream 6 Pack


This is another one of the products on this list that has a unique active ingredient. The active ingredient of the Derman antifungal cream is zinc undecylenate combined with undecylic acid. This is one of the few products on the market that uses these active ingredients.


  • These active ingredients are generally considered to be the strongest over the counter antifungal combination available
  • This product will work very well on all common fungal conditions
  • This product works relatively quickly


  • Some people may be allergic to the ingredients of this product
  • Even those who are not allergic may have side effects like redness and irritation
  • This product can be hard to find and is known to go out of stock

9) Soothe & Cool Inzo Antifungal Cream


This product features miconazole as its active ingredient, a characteristic that it shares with several other products on this list. However, it also features multiple active ingredients intended to moisturize the skin and prevent redness and irritation. This is unique amongst the products on the list, and makes it the best antifungal cream for face.


  • Moisturizing and soothing inactive ingredients will help ensure skin health and comfort
  • Miconazole is proven to be highly effective for fighting fungal conditions
  • This product also includes a slight, yet pleasant fragrance


  • This item is more expensive than some of the others on the list
  • Some may not like the fragrance
  • The packaging does not contain as much information as that of similar products

10) Kerasal Complete Care 2 in 1 Nail, Toe & Foot Antifungal Treatment Cream


This product is the only one on the list that is capable of treating toenail fungus conditions. These conditions are quite common and can be difficult to treat. This item can also treat athlete’s foot, ringworm, and jock itch. This is the best antifungal cream for feet.


  • This item can effective treat toenail fungus
  • It can also treat fungus on the toes around the nails
  • Additionally, it is effective on all of the most common fungal conditions


  • This product is slightly more complicated to use
  • It can take a relatively long time to see optimal results
  • This item is not as effective on jock itch, ringworm, and athlete’s foot as some of the other products on the list

Antifungal Creams Buyer’s Guide

When purchasing antifungals, it is important that you do the research to pick the one that is the best for you and your condition. Of course, there may be a certain amount of trial-and-error involved. This buyer’s guide below will help inform you regarding antifungals, but you still need to see which one works best for you.

Which is the Best Antifungal Medicine?

As mentioned in the introduction to the section, the best antifungal medicine depends on your condition, your body, and your skin type. This article does make note of which antifungals are targeted towards specific conditions. You may want to try out an antifungal targeted specifically towards ringworm if you have ringworm, for example.

What Are Some Side Effects of Antifungals?

The most common side effects of antifungals by far are simple redness and irritation. This is nothing to be worried about, and will go away when you discontinue using the product. In very rare instances, more severe side effects involving the internal organs may prevent present themselves. If this happens, discontinue usage and contact a physician immediately.

How Long Do Antifungals Take To Work?

How long your chosen antifungal takes to work depends on which one it is, the severity of your condition, and your skin type. Most antifungals will take between 2 to 4 weeks to completely clear a moderate antifungal condition. You may start to see with results within two to three days, or perhaps a bit longer if you are dealing with ringworm.

At What Point Should You Contact Your Doctor

If you’ve been using an antifungal for four weeks and have not seen significant improvement in your condition, it may be time to contact a doctor. If your condition has improved noticeably but has not cleared, it may be a good idea to try a different anti-fungal. It may only be worth it to contact your doctor if the condition hasn’t improved at all.

What Are Some of the Benefits of Buying Antifungals Online?

There are several benefits of buying antifungals online. The most important of which is that it is easier to do research and compare different antifungals and purchase the right one. You can also more easily read reviews of different antifungals to see how they have work for other people. Also, you can often get better prices online and you can in a brick-and-mortar store.

How Often Should You Apply the Antifungal Cream?

The frequency of application for different antifungal creams does vary somewhat. However, most will recommend that you apply the cream once or twice a day. If you apply the cream more than twice a day, you will be at a greater risk of various side effects.

Should You Combine Two Different Antifungals?

Combining two different antifungals is not a good idea and is not recommended by any medical professionals. Combining two different antifungals may not increase the effectiveness at all, and it greatly increases your chances of developing nasty side effects. Do not do this.

How Long Will an Antifungal Last Before Expiring?

Most antifungals are made to last for quite a long time before they expire. They will generally last for between 2 to 3 years, although it does vary from product to product. Either way, you will have plenty of time to use the product to treat your condition.

Should You Try Herbal Antifungals?

There are some herbal antifungals on the market that claim to be just as effective as traditional products in treating fungal conditions. There is a great deal of scientific evidence that shows that these herbal products are either totally ineffective or not as effective as traditional products. Unless your fungal condition is very minor, you should stick with your products listed in this article.

What Should You Do If You Experience Side Effects?

If you have slight redness and irritation, it is up to you whether or not you wish to discontinue usage. This is totally normal and is nothing to be worried about. However, if you have any side effects more severe than this you should discontinue use immediately. If you have any side effects involving internal organs, you should contact your physician immediately.

At What Point Do You Need to Treat Your Condition With Antifungals?

When you should begin to try antifungals is personal preference and depends on your situation. However, many people will start to use antifungals when they find themselves in a significant amount of discomfort. It may be a good idea to try antifungals as soon as you notice the condition, because it will only get worse if you do not treat it.

Should You Try Different Antifungals If the First One Doesn’t Work?

If the first antifungal you try does not work at all, you should see your doctor for a stronger prescription medicine. However, if it is somewhat effective but does not completely clear the condition, it may be a good idea to try a different antifungal.

How Can You Apply Antifungals?

All the products in this article are creams, so they are easy to apply. Simply put a small amount on the tips of your fingers and rub it into the affected area until a thin film covers the area. The product’s packaging may have more in-depth instructions.

Will There Be Pain Upon Application?

There should not be any pain upon application like there might be with some antiseptics. You may feel a slight tingling, but most people feel nothing at all when applying antifungals.

Can Antifungal Cream Be Damaged By the Shipping Process?

An antifungal cream is not fragile at all, and it is very rare for it to be damaged by the shipping process. Even if the package gets banged around, the cream will likely be fine. You only need to worry if the seal on the tube is broken. If this is the case, do not use the product.

How Can You Store Antifungal Cream?

Antifungal cream is very easy and convenient to store. It can be stored at room temperature. The most important thing is that you keep it dry. If you get the antifungal cream wet and the water gets into the cream, the product may not work properly.

Is Sharing Antifungal Cream a Bad Idea?

It may be tempting to share antifungal cream if you have a family member that has a similar problem. However, this is not recommended by any medical professionals. It can be easy for a fungal condition to spread between people if they are trying to use the same product.

Are There Any Actions You Can Take In Addition To Using Antifungals?

The most important action you can take in addition to using antifungals is to keep the affected area dry. If the area is moist, this creates the optimal conditions for fungus and will likely worsen the condition.

Which Antifungal is the Least Likely To Cause Side Effects?

The anti-fungal that is least likely to cause side effects varies from person to person and depends on the condition. Even antifungals that have the same active ingredients may have a high or a lower risk of side effects. However, products marketed as prescription strength are often more effective, yet may have a higher risk of side effects. If you know you have sensitive skin, you may want to stay away from such products if you can. If you do not have sensitive skin, you should be okay using over-the-counter products marked as prescription strength. If you have further questions, contact your physician.

Which Antifungal is the Cheapest?

Many people who have fungal conditions and need to buy antifungals are on tight budgets and would like to know which product is the cheapest. However, there is not any one answer to this. The prices of different products vary widely. However, they are usually within the same general range. Usually, it is between $6 to $7 for a tube of anti-fungal cream, no matter what the active ingredient is. You can usually get antifungals for cheaper if you buy them in bulk. However, if you do this you run the risk of not actually needing all the product that you have purchased.




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